Vitamin D is formed under the influence of sunlight. In summer, 10-15 minutes are enough for a daily dose, but in winter in the northern countries there is not enough sun. Therefore, people use supplements to avoid deficiency.
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Scientists from the McCaig Institute for Bone and Joint Health in Canada conducted an experiment with 300 volunteers aged 55 to 70 years, according to JAMA Nerwork.
Participants were divided into three groups: the first received a daily dose of 400 IU omega-3, the second – 4000 IU, and the third – 10,000 IU.
High precision computed tomography (XtremeCT) measured bone density and strength on the wrist and in the bones. After all, the main research parameter is bone mineral density (MSCT), which determines the ability of bones to withstand loads and not break. The older a person is, the lower his MSCT score.
Therefore, the researchers performed dual-energy x-ray densitometry, the most accurate way to measure bone density.
Bone density was measured at the beginning of the study, as well as at the sixth, 12th, 24th and 36th month from the start of the study. The researchers also took blood and urine tests.
The results of the study showed a decrease in mineral density over time in all three groups of subjects. However, the larger the daily dose of vitamin D, the greater the decrease in density.
In the first group receiving the minimum dose, MSCT decreased by 1.4% over three years, in the second group – by 2.6%, and in the third – by 3.6%.
The participants of the second and third groups had an increased risk of ipercalciuria – an increased concentration of calcium salts in the urine and is one factor in the development of urolithiasis. This risk increased in the second group by 22%, in the third – by 31%.
Scientists note: a dose of 400 IU is justified and sufficient for healthy people, and doses of about 4000 IU and higher are not recommended for bone pathologies.
In no case do not self-medicate and consult a doctor.
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