It is about drugs with the active substance nifedipine, which are mainly used to treat high blood pressure and angina, writes EurekAlert !.
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Angina – what is it? This is a heart disease, accompanied by pain or discomfort in the chest. It occurs when the heart muscle does not receive enough oxygen-rich blood through the coronary arteries.
The results of the study showed that the use of high doses of this substance is associated with an increased risk of heart failure. At the same time, this side effect was not found in drugs containing amlodipine.
According to scientists, nifedipine and amlodipine are often used by many cardiologists and other doctors in the treatment of heart disease. Prior to this, both drugs were considered equally effective and safe.
An experiment showed that high doses of nifedipine may increase the risk of sudden cardiac arrest, while amlodipine is really safe. These results may have to be taken into account when prescribing a particular drug. Sudden cardiac arrest is a common cause of death in the developed world.
By the way, on the website "Drug Control" in Ukraine registered 19 drugs with the active substance nifedipine.
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