Scientists have identified a group of cells sensitive to nicotine in the midbrain of mice. These neurons called Amigo1, they contain protein receptors that bind to the substance when it enters the brain with the bloodstream, writes Science Alert.
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With long-term use of nicotine, Amigo1 cells accumulate. By suppressing their activity, it is possible to combat the burden of smoking, the researchers said.
Found a brain area that affects nicotine addiction
They came to this conclusion as a result of the experiment. Laboratory mice six weeks watered with water with a solution of alkaloids. In a group of animals, scientists "put down" the genes that activate the nicotinic receptors. Then the mice were released into the rooms where the drinkers with the narcotic liquid stood. Animals with active Amigo1 ran to the drinkers, but with the genes turned off, they showed no interest in them.
Now scientists are planning to do research with people.
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