The exosome protein CEMIP is responsible for the transfer of cancer cells to the brain. Now doctors are working on a drug that will prevent the formation of metastases, writes Nature.
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According to scientists, it is CEMIP that provokes inflammation in the blood vessels and resident immune cells of the brain. This contributes to the survival and growth of cancer cells, which lead to the appearance of tumors in the brain.
Scientists have found how to prevent the formation of metastases in the brain
Scientists investigated and found that a high CEMIP indicates a high risk of metastasis in the brain, mammary gland, and lungs.
Specialists immediately began to look for a way that will help slow down or completely stop the formation of this protein. During laboratory experiments on animals, they eliminated CEMIP and found that the removal of this protein prevents cancer cells from "colonizing" the brain.
A team of scientists has teamed up with several therapeutic institutes and cancer centers to develop CEMIP diagnostics, as well as create antibodies that will block this protein.
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