Halichondrin, a very strong natural antioxidant, was found in sea sponges 33 years ago, and since then, scientists have repeatedly tried to reproduce this substance under laboratory conditions as a drug formula.
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But only now the international team of specialists managed to synthesize the long-awaited medicine. This is stated on the website of Harvard University.
Galichondrin can destroy the components of the microenvironment of the tumor, due to which the transformation of healthy cells into malignant occurs. It is known that under his influence the formation of structures involved in the division of cancer cells is stopped.
Galichondrin extracted from sea sponges
Before that, in 1992, scientists developed a simplified version of halichondrin, which remotely resembled an analogue in composition. This substance is still used to treat metastatic breast cancer and liposarcoma.
This time, according to the authors of the study, they managed to get 11.5 grams of a substance with a purity of 99.81% – this should be enough for conducting a clinical study of the drug in humans.
The molecule they developed was called E7130B, it was tested in experiments conducted in vitro (in vitro) and in vivo (in animal models). These tests have shown that the substance can successfully treat cancer.
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