French scientists from the Pasteur Institute found that an immune response is formed when solid foods are introduced into the diet.
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Experiments in rodents indicate that the first feeding is crucial for the formation of the intestinal immune response and the entire immune system. In humans, the process is the same, scientists are sure.
How was the study
The team came to this conclusion after experiments on mice. This mechanism has a specific time interval of two to four weeks in mice, which corresponds to the age of three to six months in humans.
Immunity forms in early childhood / Photo: Unsplash
To test the programmedness of the mechanism over time, scientists gave mice antibiotics during this period, and then evaluated the consequences.
After the destruction of the microbiota with antibiotics, the immune response no longer arose. After treatment, mice are more likely to develop inflammatory diseases: colorectal cancer, colitis and intestinal allergies.
Such results confirm the fact that in early childhood the probable propensities for inflammatory disorders are determined.
The first meal is important for the formation of the immune system / Photo: Unsplash
The immune response is of great importance, as it is involved in the formation of the immune system, which protects against inflammatory diseases. If a failure occurs, the likelihood of developing autoimmune diseases and cancer increases.
The team also determined that regulatory T cells play a key role in a balanced immune response. Without them, immune reactions are exacerbated, which leads to inflammatory diseases.
The results indicate a significant influence of the state of microbiota at an early age on the functioning of the immune system. Now, researchers plan to study the effects of early weaning from breastfeeding. Mostly, they will assess the possible risks of neurodegenerative diseases.